- 中文名称
人Enolaseα抑制剂筛选试剂盒(比色)
- 英文名字
- Human Enolase α Inhibitor Screening Kit (Colorimetric)
- 供应商
- Biovision
- 产品货号
- K526-100
- 产品报价
- ¥询价/100assays

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- 待更新
- 产品描述
- Enolase (EC 4.2.1.11), also called 2-Phospho-D-glycerate hydrolase, is a key enzyme in glycolysis. It converts 2-phosphoglycerate into phosphoenolpyruvate (PEP). It also catalyzes the reverse reaction, PEP to 2-phosphoglycerate under anabolic conditions during gluconeogenesis. In mammals, three genes encode for the Enolase α, β and γ isoforms. These isoforms combine together to form both homo and heterodimeric complexes resulting in five isozymes, three of which are commonly found in human tissues. Enolase α, also called enolase 1, exists in variety of tissues which can undergo glycolysis. Besides its role in glycolysis, increased Enolase α activity is associated with tumor invasion and metastasis; therefore, screening for novel and specific inhibitor of enolase α inhibitor may be of great interest for tumor treatment. In BioVision’s Human Enolase α Inhibitor Screening Kit, Enolase α catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate, which is subsequently used to generate an intermediate product. The intermediate product stoichiometrically reacts with OxiRed™ probe generating a colorimetric signal (OD 570 nm). In the presence of Enolase α inhibitor, the reaction is impeded. An enolase α Inhibitor Control is included to compare the efficacy of the sample inhibitors. The assay is simple, fast, high-throughput adaptable and can be completed in less than 1 hr
- 产品特点
- • Rapid and easy-to-use.
• High-throughput adaptable
• This assay kit can be used for initial screening of compounds as anti-Enolase
- 保存建议
- -20
- 其他
- BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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