- 中文名称
流感神经氨酸酶抑制剂敏感性测定试剂盒
- 英文名字
- Influenza Neuraminidase Inhibitor Susceptibility Assay Kit
- 供应商
- Biovision
- 产品货号
- K524-1000
- 产品报价
- ￥询价/1000assays
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868.
- 产品新闻
- 背景资料
- 待更新
- 产品描述
- Neuraminidase (EC 3.2.1.18) is a tetrameric Ca2+-dependent sialidase enzyme that cleaves α-glycosidic linkages of terminal sialic acid residues from the oligosaccharide chains of glycoproteins. Neuraminidase-family enzymes are present in most lifeforms, from bacteria to humans, and are also encoded by several viral genomes, including influenza viruses. Influenza neuraminidase plays a critical role in replication and transmission of the virus by preventing self-aggregation of replicating progeny viral particles and enabling release of active influenza virions from infected host cells. Neuraminidase inhibitors, which competitively block the enzyme-mediated release of newly synthesized viral particles, are widely used as anti-influenza drugs. Rapid mutation of viral neuraminidase can yield new influenza strains that are more pathogenic and also engender resistance to existing neuraminidase inhibitors. Hence, monitoring of neuraminidase activity and inhibitor susceptibility in influenza field isolates collected worldwide is integral to identifying new pandemic influenza strains and guiding public health strategies to control seasonal influenza epidemics. BioVision’s Influenza Neuraminidase Activity/Inhibitor Susceptibility Assay Kit enables rapid measurement of viral neuraminidase activity, utilizing a fluorogenic substrate that is converted into a stable, highly fluorescent product (Ex/Em = 368/460 nm). The assay allows for high-throughput functional screening of baseline neuraminidase activity and inhibitor susceptibility patterns in influenza virus isolates in order to evaluate the possible emergence of new inhibitor-resistant strains. A straightforward, standardized protocol consistent with the latest CDC and WHO research guidelines ensures reproducible neuraminidase inhibitor IC50 data for influenza antiviral susceptibility surveillance. The assay may also be used for screening of novel neuraminidase inhibitors against known drug-resistant influenza strains. The kit includes sufficient reagents to perform at least 1000 reactions (ten assay plates) in a 96-well plate format
- 产品特点
- • Simple, rapid & convenient
• The assay may also be used for screening of novel neuraminidase inhibitors against known drug-resistant influenza strains.
- 保存建议
- -20
- 其他
- BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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