ICOS Ligand (ICOSL) is the ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype. BioVision’s ICOSL ELISA kit is a sandwich ELISA assay for the quantitative measurement of Mouse ICOSL in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of Mouse ICOSL captured from the samples.
产品特点
Easy, convenient and time-saving method to measure the level of ICOSL in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids.
Detection Range: 0.156-10 ng/ml
Sensitivity: < 0.094 ng/ml
