CD 25(IL-2 R α)是白细胞介素2受体α链的55 kDa亚基,已显示其在淋巴细胞分化、活化和增殖中发挥作用。IL-2 R α是一种跨膜糖蛋白,由高度糖基化的胞外结构域、跨膜区和短胞质尾区组成。IL-2 R α与IL-2 R β(CD 122)和IL-2 R γ(CD 132)异源二聚化,形成IL-2受体复合物。IL-2 R α本身以相对低的亲和力结合IL-2,而IL-2受体复合物以高亲和力结合IL-2。IL-2 R α突变导致严重免疫缺陷。 抗人CD 25(7 G7 B6)抗体原液-超低内毒素该产品同种型对照:Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245) 缓冲液:ICH3001-100ml,nICH3002-100ml,nICH3003-100ml, 浓度:1.0 – 5.0 mg/ml 纯度:>98% by SDS-PAGE and HPLC 内毒素:≤ 0.5 EU/mg as determined by the LAL method 制剂:This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
应用类型
ELISA, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot
免疫原
Recombinant human peripheral blood mononuclear cells (PBMCs)