TCRβ抗体（克隆H57-597）识别αβ胸腺细胞和T淋巴细胞以及自然杀伤T（NKT）细胞上表达的T细胞受体（TCRβ）的β链。TCRβ是一种跨膜蛋白，由氨基末端可变区、恒定区和通过二硫键与TCR α链（TCRα）共价连接的茎段组成。TCRα/β不含信号传导结构域，而是与TCR信号传导所必需的CD 3复合物（TCR-CD 3）非共价结合。TCRα/β识别与主要组织相容性复合体（MHC）分子结合的抗原，导致CD 3 ITAM磷酸化和随后的T细胞活化、增殖和存活。 抗小鼠TCR β（H57-597）抗体体内抗体-低内毒素该产品同种型对照：Armenian Hamster IgG Isotype Control for In Vivo - Ultra Low Endotoxin [PIP] (ICH2251UL) 缓冲液：ICH3001-100ml，nICH3002-100ml，nICH3003-100ml， 浓度：≥ 5.0 mg/ml 纯度：≥95% monomer by analytical SEC, >95% by SDS Page 内毒素：<1.0 EU/mg as determined by the LAL method 制剂：This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
