CD 279,也称为程序性死亡-1(PD-1),是一个50-55 kD的免疫球蛋白超家族成员。PD-1在CD 4-CD 8-胸腺细胞的亚群上以及在活化的T和B细胞上表达。PD-1配体PD-L1(也称为B7-H1)和PD-L2(B7-DC)是B7免疫球蛋白超家族的成员。据报道,这种RMP 1 -14抗体可阻断PD-1与其配体(B7-H1和B7-DC)的结合,并抑制T细胞增殖和细胞因子产生。 抗PD-1(RMP 1 -14)该产品同种型对照:Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244) 缓冲液:ICH3001-100ml,nICH3002-100ml,nICH3003-100ml, 浓度:1.0 - 5.0 mg/ml 纯度:>95% by SDS-PAGE and HPLC 内毒素:≤ 1.0 EU/mg as determined by the LAL method 制剂:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
应用类型
Western Blot, Blocking, Flow Cytometry, Functional Assays