CD 152,也称为CTLA-4或Ly-56,在氨基酸序列、结构和基因组组织方面与CD 28具有显著的相似性。此外,CD 152和CD 28共享共同的B7家族反受体。与CD 28不同,CD 152的表达似乎仅限于活化的T细胞和CD 25 + CD 4+调节性T(Treg)细胞。CD 152被认为在免疫耐受的诱导和维持以及保护性免疫和胸腺细胞调节的发展中起作用。 抗小鼠CTLA-4(UC 10 - 4F 10 -11)体内抗体-超低内毒素该产品同种型对照:Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251) 缓冲液:ICH3001-100ml,nICH3002-100ml,nICH3003-100ml, 浓度:≥ 2.0 mg/ml 纯度:>98% by SDS-PAGE and HPLC 内毒素:≤ 0.5 EU/mg as determined by the LAL method 制剂:0.01 M phosphate buffered saline (PBS) pH 7.4, without BSA or sodium azide added.
应用类型
Flow Cytometry, Western Blot, Functional Assays, Immunoprecipitation
免疫原
Purified Recombinant Mouse CTLA4 Fc Fusion Protein