- 中文名称
Interleukin 33 ELISA Kit, BioAssay (IL-33)
- 英文名字
- Interleukin 33 ELISA Kit, BioAssay (IL-33)
- 供应商
- USBiological
- 产品货号
- I8443-92Z
- 产品报价
- ￥1/96Tests
- 产品说明书
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- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- For the quantitative determination of Human IL-33 levels in serum or other biological samples.*Buffers, Substrates and Plates are not included.Interleukin-1 (IL-1) family members, such as IL-19 and IL-18, play important roles in host defense, immune regulation, neuronal injury and inflammation (1, 2). Recently, a new member of this family, IL-33, has been reported. It mediates its biological effects via IL-1 receptor ST2 and activates NF-kB and MAPK pathways (3). IL-33 is synthesized in response to cytokines such as IL-1, and plays an important role in TH2-associated immunology. IL-33 expression drives production of TH2-associated cytokines from in vitro polarized TH2 cells and induces the expression of IL-4, IL-5, and IL-13 in vivo. Overexpression of IL-33 in mice leads to severe pathological changes in mucosal organs. IL-33 was previously identified as NF-HEV, a nuclear factor preferentially expressed in high endothelial venules HEV) (4). Recent studies revealed that IL-33 is a heterochromatin-associated nuclear factor and endothelial cells constitute a major source of IL-33 mRNA in chronically inflamed tissues from patients with rheumatoid arthritis and Crohn's disease(5). These data indicate that IL-33 is a dual function protein that may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties. The human IL-33 is expressed with a prodomain (aa 1-111) that is cleaved by caspase-1 to produce a 18kD protein (112-270) (6).Kit Contents: I8443-92Z1: Coating Antibody 1x80ulContains affinity-purified Chicken anti-human IL-33 at 1mg/ml.I8443-92Z2: Calibrator 1x4ul Contains Recombinant human IL-33 Antigen at 1mg/ml.Working Range: 500–0.7ng/mlI8443-92Z3: HRP Detection Antibody 1x12ulContains affinity-purified Chicken anti-human IL-33–HRP Conjugate at 0.6mg/ml.Buffers, Substrates and Plates are not included.Storage and Stability: For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- 产品特点
- 针对Interleukin 33 ELISA Kit, BioAssay (IL-33)该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到Interleukin 33 ELISA Kit, BioAssay (IL-33)产品后将其置于4°C/-20°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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