- 中文名称
IGF1, Human, BioAssay Kit (Insulin-like Growth Factor I, IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IBP1)
- 英文名字
- IGF1, Human, BioAssay Kit (Insulin-like Growth Factor I, IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IBP1)
- 供应商
- USBiological
- 产品货号
- I7661-11P
- 产品报价
- ￥1/1Kit
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- Insulin-like growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. Human IGF-I is synthesized as two precursor isoforms with N- and alternate C-terminal pro-peptides. These isoforms are differentially expressed by various tissues. The 7.6kD mature IGF-I is identical between isoforms and is generated by proteolytic removal of the N- and C-terminal regions. Mature human IGF-I shares 94% and 96% aa sequence identity with mouse and rat IGF-I, respectively, and exhibits cross-species activity. It shares 64% aa sequence identity with mature human IGF-II. Circulating IGF-I is produced by hepatocytes, while local IGF-I is produced by many other tissues in which it has paracrine effects.1 IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. IGF-I regulates glucose and fatty acid metabolism, steroid hormone activity, and cartilage and bone metabolism. It plays an important role in muscle regeneration and tumor progression. IGF-I binds IGF-I R, IGF-II R, and the insulin receptor, although its effects are mediated primarily by IGF-I R.9 IGF-I association with IGF binding proteins increases its plasma half-life and modulates its interactions with receptors.Intended Use:Designed to qualitatively and quantitatively determine the presence of cells expressing IGF-I receptors or other interacting proteins by flow cytometry.Specificity:HumanTest Principle:Washed cells are incubated with the biotinylated protein that in turn binds to the cells via specific cell surface receptors or other interacting proteins. The cells are then directly incubated with avidin-fluorescein, which attaches to the bound biotinylated protein. Cells expressing the receptor/interacting protein are fluorescently stained, with the intensity of staining proportional to the density of such protein. Relative density is then determined by flow cytometry using 488nm wavelength laser excitation.Kit Components:Recombinant human IGF-I conjugated to Biotin: 1x100 reactionsAvidin-Fluorescein: 1x2mlNegative Control Reagent: 1x600ulBlocking Antibody: 1x15 reactionsCell Wash Buffer (10 X): 1x60mlStorage and Stability:See Kit Protocol for detailed storage instructions.
- 产品特点
- 针对IGF1, Human, BioAssay Kit (Insulin-like Growth Factor I, IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IBP1)该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到IGF1, Human, BioAssay Kit (Insulin-like Growth Factor I, IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IBP1)产品后将其置于-20°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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