- 中文名称
IKKa/b, phosphorylated (Ser176/180) Antibody Sampler Kit, BioAssay
- 英文名字
- IKKa/b, phosphorylated (Ser176/180) Antibody Sampler Kit, BioAssay
- 供应商
- USBiological
- 产品货号
- I3000-11B
- 产品报价
- ￥1/1Kit
- 产品说明书
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- 购买方式
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- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- Intended Use:The Phospho-IKKa/b (Ser176/180) Antibody Sampler Kit contains reagents to examine protein levels of IKKa when phosphorylated at Ser176/180 and IKKb when phosphorylated at Ser177/181. The kit contains primary and secondary antibodies to perform four Western Blots with each antibody.Background: The NF-κB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IκB proteins (1-3). Most agents that activate NF-κB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degrada- tion of IκB (3-7). The key regulatory step in this pathway involves activation of a high molecular weight IκB kinase (IKK) complex, whose catalysis is generally carried out by three tightly associated IKK subunits. IKKa and IKKb serve as the catalytic subunits of the kinase. IKKγ serves as the regulatory subunit (8-9). Activation of IKK depends on phosphorylation; Ser177 and Ser181 in the activation loop of IKKb (176 and 180 in IKKa) are the specific sites whose phosphorylation causes conformational changes resulting in kinase activation (10-13).Kit Components:1. Phospho-IKKa (Ser176)/IKKb (Ser177) (C84E11) Mab rabbit x human, 1x20ul2. Phospho-IKKa/b (Ser176/180) (16A6) Mab rabbit x human, 1x20ul3. Phospho-IKKa/b (Ser176/180) Pab rabbit x human, 1x20ul4. IgG (HRP) Pab Goat x Rabbit, 1x100ulApplications: Suitable for use in Western Blot. Phospho-IKKa/b (Ser176/180) (16A6) Mab rabbit x human has been tested in Immunohistochemistry (frozen and paraffin). Other applications not tested.Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- 产品特点
- 针对IKKa/b, phosphorylated (Ser176/180) Antibody Sampler Kit, BioAssay该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到IKKa/b, phosphorylated (Ser176/180) Antibody Sampler Kit, BioAssay产品后将其置于-20°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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