- 中文名称
IkB alpha (Ser32) Antibody BioAssay Phosphorylation Detection Kit discontinued
- 英文名字
- IkB alpha (Ser32) Antibody BioAssay Phosphorylation Detection Kit discontinued
- 供应商
- USBiological
- 产品货号
- I2500-01A
- 产品报价
- ￥1/1Kit
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- The NF-kB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IkB proteins (1–3). Activation occurs via phosphorylation of IkB-a at serine 32 and 36, resulting in the release and nuclear translocation of active NF-kB (3–7). IkB-a phosphorylation and resulting reldependent transcription are activated by a highly diverse group of extracellular signals, including inflammatory cytokines, growth factors, and chemokines. Phosphorylation of IkB-a at Serine 32 and 36 has been shown to stimulate conjugation with ubiquitin followed by proteasome-mediated degradation of IkB, resulting in the release of active NF-kB. The kinases that phosphorylate IkB at these activating sites are as yet poorly understood, although one recent report implicates a large complex that appears to be dependent upon ubiquitination for activity (7). As phosphorylation of IkB-a at Ser32 is essential for release of active NF-kB, phosphorylation at this site is an excellent marker of NF-kB activity.Kit Components:I2500-01A3: IkB alpha Control Cell Extract (untreated) 1x200ul I2500-01A5: Biotin (HRP) 1x100ul I2500-01A6: LumiGLO® Reagent 20X 1x5mlI2500-01A7: Peroxide 20X 1x5ml I2500-01A8: Protein MW Marker, Detection (Biotin) 1x100ul I2500-01A9: IkB alpha Control Cell Extract (treated)1x200ulI2500-01A10: IkB alpha Phosphorylated (Ser32) Mab Mouse 1x100ul I2500-01A11: IkB alpha Mouse Mab1x100ulI2500-01A12: IgG (HRP) Eq x Mo 1x50ulApplications: Suitable for use in Western Blot. Other applications not tested.Recommended Dilution:Western blot: 1:1000 Optimal dilutions to be determined by the researcher.Storage and Stability:May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- 产品特点
- 针对IkB alpha (Ser32) Antibody BioAssay Phosphorylation Detection Kit discontinued该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到IkB alpha (Ser32) Antibody BioAssay Phosphorylation Detection Kit discontinued产品后将其置于-20°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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