HSPH1 analysis is used as an indicator and as a diagnostic aid in problematic lesions.
HSPH1 chaperones the responses to endoplasmic reticulum （ER） stress during its interactions with GRP78 and GSK3， and without HSP105 cell death following ER stress proceeds by a non-caspase-3-dependent process.
HSPH1 is highly expressed in a variety of human tumors.
HSPH1 is a mammalian member of the HSP105/110 family， a diverged subgroup of the HSP70 family. HSP105 has 2 isoforms， alpha and beta. Hsp105a associates with Hsp70/Hsc70 as complexes in vivo and regulates the chaperone activity of Hsp70/Hsc70 negatively in vitro and in vivo.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile filtered colorless solution. The HSP105 protein solution contains 20mM Tris-HCl， pH-8 and 50mM NaCl.
保存建议
Store at 4℃ if entire vial will be used within 2-4 weeks.
Store， frozen at -20℃ for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles.
