EXO2 is a 3’-to-5’ exonuclease specific for small(primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. RNA Exonuclease 2(REXO2) takes part in DNA repair, replication, and recombination, and in RNA processing and degradation. EXO2 is involved in resistance of human cells to UV-C-induced cell death via its part in the DNA repair process.