NADH dehydrogenase [ubiquinone] iron-sulfur protein 3（NDUFS3) is a member of the complex I 30 kDa subunit family. NDUFS3 is one of the iron-sulfur protein（IP) components of mitochondrial NADH:ubiquinone oxidoreductase（complex I). This complex is the first enzyme complex in the electron transport chain of mitochondria. The iron-sulfur protein（IP) fraction of complex I consists of seven subunits. NDUFS3 gene mutations are linked with Leigh syndrome resulting from mitochondrial complex indefficiency.
