WARS is part of the class I tRNA synthetase family. 2 types of tryptophanyl tRNA synthetase exist, a cytoplasmic form, called WARS, and a mitochondrial form, called WARS2. WARS catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. WARS controls ERK, Akt, and eNOS activation pathways that are related with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
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大肠杆菌中重组表达
溶解建议
提供的人色氨酰-tRNA合成酶(WARS)产品为过滤灭菌的无色溶液;其中1mg/ml人人色氨酰-tRNA合成酶(WARS)产品溶解于20mM Tris pH 8, 1mM DTT, 0.1M NaCl, 1mM DTT,10%甘油溶液中.