GALE is an enzyme that participates as the third enzyme in the Leloir pathway of galactose metabolism. GALE is a homodimeric epimerase localized in bacterial， plant， and mammalian cells. GALE inhances the reverse chemical reaction， the conversion of UDP-glucose to UDP-galactose. UDP-galactose builds galactose-containing proteins and fats， which have a crucial part in chemical signaling， building cellular structures， transporting molecules， and producing energy.
