DDT is an enzyme that catayzes the tautomerization of D-dopachrome to give 5,6-dihydroxyindole(DHI). DDT is part of the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. DDT shares a homologous amino acid sequence(33% identical) with MIF and has similar tautomerase activity. DDT functions a proinflammatory cytokine.