TP53I3 participates in the generation of reactive oxygen species（ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity， with a preference for 1，2-naphtoquinone over 1，4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity（in vitro). TP53I3 is localized to the cytoplasm and induced in primary， non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.
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来源宿主
大肠杆菌中重组表达
溶解建议
提供的人肿瘤蛋白p53可诱导蛋白3（TP53I3）产品为过滤灭菌的无色溶液；其中人肿瘤蛋白p53可诱导蛋白3（TP53I3）产品溶解于20mM Tris HCL pH 8， 0.1M NaCl， 1mM DTT，20%甘油溶液中.
