NDUFS4 is a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase(Complex I), the primary multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I is involved in cellular ATP production, the main source of energy for numerous vital processes in living cells. NDUFS4 removes electrons from NADH and passes them by a series of diverse protein-coupled redox centers to the electron acceptor ubiquinone. NDUFS4 presents a hotspot of mutations in the genetic apparatus of oxidative phosphorylation and the correct assembly of the subunit it encodes is essential for completion of the assembly of complex I.
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来源宿主
大肠杆菌中重组表达
溶解建议
提供的人组氨酸脱氢酶铁硫蛋白-4(NDUFS4)产品为过滤灭菌的无色溶液;其中人组氨酸脱氢酶铁硫蛋白-4(NDUFS4)产品溶解于20mM Tris pH 8,30%甘油溶液中.