PPIF is a part of the peptidyl-prolyl cis-trans isomerase(PPIase) family. PPIF accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIF is key component of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
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大肠杆菌中重组表达
溶解建议
提供的人肽基脯氨酰顺反异构酶-F(PPIF)产品为过滤灭菌的无色溶液;其中人肽基脯氨酰顺反异构酶-F(PPIF)产品溶解于20mM Tris pH 7.5, 10%甘油,1mM DTT溶液中.