Cathepsin D is synthesized as a 54kDa precursor， which is proteolytically processed to an intermediate 48kDa single chain， which matures into more stable 34kDa and 14kDa two chain form. It is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane， extracellular matrix， and xonnective tissue. Because of its mitogenic and proteolytic activities， it has been implicated as a prognostic marker in many tumor types. Cathepsin D is expressed in epithelial cells as well as in macrophages.
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该【CTSD】重组人组织蛋白酶-DRecombinant Human Cathepsin-D是Prospec品牌中国区域代理商艾美捷科技产品，具体的蛋白序列可查看提供的英文版本产品说明书。
