Activated Protein C exerts an antithrombotic effect by inhibiting Factors Va and VIIIa.
In vitro data indicate that Activated Protein C has indirect profibrinolytic activity through its ability to inhibit plasminogen activator inhibitor-1（PAI-1) and limiting generation of activated thrombin-activatable-fibrinolysis-inhibitor. Additionally， in vitro data indicate that Activated Protein C may exert an anti-inflammatory effect by inhibiting human tumor necrosis factor production by monocytes， by blocking leukocyte adhesion to selectins， and by limiting the thrombin-induced inflammatory responses within the microvascular endothelium.
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该【APC】重组活化蛋白CRecombinant Human Ribophorin II是Prospec品牌中国区域代理商艾美捷科技产品，具体的蛋白序列可查看提供的英文版本产品说明书。
