THTPA enzyme is part of the THTPase family. THTPA is localized to the cytoplasm and expressed at small quantities in a variety of tissues， including testis， uterus， prostate， bladder， lung and kidney. THTPA is a hydrolase that catalyzes the H2O-dependent hydrolysis of thiamine triphosphate（THTP) to thiamine diphosphate（THDP)， the main form of thiamine within the cell. THTPA occurs as a monomer and is activated at an optimal pH of 8.5.
