HDAC2 is a member of the histone deacetylase family that performs through the construction of large multiprotein complexes and are in charge of the deacetylation of lysine residues on the N-terminal region of the core histones. HDAC2 forms transcriptional repressor complexes by relating to a diversity of proteins， like YY1- a mammalian zinc-finger transcription factor.
In addition， HDAC2 has a vital part in transcriptional regulation， cell cycle progression and developmental procedures.
