Inorganic pyrophosphatase（ppa) is a member of the Ppase family. PPA is an enzyme which catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. Since this is a highly exergonic reaction， it can therefore be coupled to unfavorable biochemical transformations in order to drive these transformations to completion. The role of the PPA enzyme is a critical one in the lipid metabolism（including lipid synthesis and degradation)， calcium absorption and bone formation， DNA synthesis， as well as other biochemical transformations.
