Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1 3 4-trisphosphate (Ins(1 3 4)P3) is an intermediate in the inositol phosphate pathway. Ins(1 3 4)P3 inhibits Ins(3 4 5 6)P4 1-kinase which regulates Ins(3 4 5 6)P4 levels. Ins(3 4 5 6)P4 in turn is responsible for inhibiting calcium-activated chloride channels. Ins(1 3 4)P3 is produced by dephosphorylation of Ins(1 3 4 5)P4 by a 5-phosphatase. Ins(1 3 4)P3 is a substrate for phosphatases yielding Ins(1 3)P2 and Ins(3 4)P2. Powered by Bioz See more details on Bioz