类异戊二烯化合物是一组不同的天然产物，是所有细胞的必需成分。类异戊二烯由简单的前体异戊烯基二磷酸（IPP）和二甲基烯丙基二磷酸（DMAPP）生物合成。真核真菌和一些革兰氏阳性细菌通过甲羟戊酸（MVA）途径产生IPP，而革兰氏阴性和一些革兰氏阳性细菌利用非甲羟戊酸或2-C-甲基-D-β-4-磷酸（MEP）途径。2 Z 6 E-法呢基二磷酸是由（2 Z 6 E）-法呢基二磷酸合酶催化IPP与香叶基二磷酸（GPP）缩合而成。Z-FPP是在分枝杆菌细胞壁的生物合成中具有核心作用的癸烯基二磷酸的前体。
产品描述
Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes fungi and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. 2Z 6E-farnesyl diphosphate is formed by (2Z 6E)-farnesyl diphosphate synthase catalyzed condensation of IPP with geranyl diphosphate (GPP). Z-FPP is the precursor of decaprenyl diphosphate which has a central role in the biosynthesis of the mycobacterial cell wall.
