Wortmannin is a specific irreversible inhibitor of phosphatidylinositol 3-kinases (IC50 ~ 2-3 nM). It shows similar potency for all classes of PI3Ks.Publications Powered by Bioz See more details on Bioz1. Takahashi K Tanaka T Suzuki K. Directional control of WAVE2 membrane targeting by EB1 and phosphatidylinositol 3 4 5-triphosphate. Cell Signal. 2010;22(3):510-8.