IFN-gamma is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. BioVision’s IFN-gamma ELISA kit is a sandwich ELISA assay for the quantitative measurement of IFN-gamma in Rat serum, plasma and cell culture supernatants. The density of color is proportional to the amount of IFN-gamma captured from the samples.
产品特点
Easy, convenient and time-saving method to measure the level of IFN-gamma in serum, plasma, tissue homogenates, culture supernatants and other biological fluids.
Detection Range: 31.25 - 2000 pg/ml
Sensitivity: < 18.75 pg/ml
Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10%
No significant cross-reactivity or interference was observed.
