Apoptosis regulator (BAX) accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BioVision’s BAX ELISA kit is a sandwich ELISA assay for the quantitative measurement of BAX in rat serum, plasma and cell culture supernatants. The density of color is proportional to the amount of BAX captured from the samples.
产品特点
Easy, convenient and time-saving method to measure the level of BAX in rat serum, plasma, tissue homogenates, culture supernatants and other biological fluids.
Detection Range: 0.313 - 20 ng/ml
Sensitivity: < 0.188 ng/ml
Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10%
This assay has high sensitivity and excellent specificity for detection of BAX. No significant cross-reactivity or interference between BAX and analogues was observed.
