8-hydroxy-2'-deoxyguanosine (8-OHdG) is an oxidized derivative of deoxyguanosine. Concentrations of 8-oxo-dG within a cell are a measurement of oxidative stress. It is considered as a critical biomarker of oxidative stress and carcinogenesis. This ELISA kit uses Competitive-ELISA as the method. The microtiter plate provided in this kit has been pre-coated with 8-OHdG. During the reaction,8-OHdG in the sample or standard competes with a fixed amount of 8-OHdG on the solid phase supporter for sites on the Biotinylated Detection Antibody specific to 8-OHdG. BioVision’s 8-OHdG ELISA kit is a sandwich ELISA assay for the quantitative measurement of Mouse 8-OHdG in serum, plasma and cell culture supernatants in 90 minutes. The density of color is proportional to the amount of Mouse 8-OHdG captured from the samples.
产品特点
Easy, convenient and time-saving method to measure the level of 8-OHdG in mouse serum, plasma, urine, cell culture samples, tissue samples.
Detection Range: 15 – 1350 pg/ml
Sensitivity: < 4.5 pg/ml