- 中文名称
BioSim™抗利妥昔单抗(Mabthera®)(人类)ELISA试剂盒
- 英文名字
- BioSim™ anti-Rituximab (Mabthera®) (Human) ELISA Kit
- 供应商
- Biovision
- 产品货号
- E4385-100
- 产品报价
- ¥询价/100assays
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868.
- 产品新闻
- 背景资料
- 待更新
- 产品描述
- Rituximab (Mabthera®) is a genetically engineered chimeric murine/human monoclonal antibody specific to CD20. CD20 is an approximately 35 KDa transmembrane phosphoprotein involved in the activation, proliferation, and differentiation of B-lymphocytes. It is absent in terminally differentiated plasma cells. The Fab domain of rituximab binds to the CD20 antigen on B-lymphocytes and the Fc domain recruits immune effector functions to induce apoptosis in B cells. It is used in treating leukemias and lymphomas, some autoimmune disorders, and organ transplant. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. BioVision’s BioSimTM anti-Rituximab ELISA kit is designed to quantify/measure the antibody against Rituximab with high specificity and sensitivity in biological matrices.
- 产品特点
- Easy, convenient, sensitive and time-saving method to measure the level of antibody against Rituximab in human serum and plasma.
Detection Range: 62 - 500 ng/ml
Sensitivity: 30 ng/ml
Assay Precision: Intra-Assay: CV < 15%; Inter-Assay: CV < 15% (CV (%) = SD/mean X 100)
Cross Reactivity: Rituximab (Rituxan®, Mabthera®) infusion camouflages/masks the presence of antibody to rituximab (ATR) in serum/plasma samples. Therefore, blood sampling time is critical for detection of ATR. It is convenient to obtain blood sample just before the infusion or at least 2 weeks after the infusion of Rituximab (Rituxan®, Mabthera®)
Recovery rate: 85 – 115% with normal human serum samples with known concentrations
- 保存建议
- 4
- 其他
- BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理,艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
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- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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