Creatine Kinase， Mitochondrial 2 （CKMT2） is a member of the ATP:guanido phosphotransferase family. CKMT2 is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier， creatine. CKMT2 reversibly catalyzes the transfer of phosphate between ATP and various phosphogens （e.g. creatine phosphate）. Creatine kinase isoenzymes have a principal role in energy transduction in tissues with large， variable energy demands， such as skeletal muscle， heart， brain and spermatozoa. Mitochondrial creatine kinase occurs in 2 different oligomeric forms: dimers and octamers， contrary to the exclusively dimeric cytosolic creatine kinase isoenzymes. The CKMT2 gene contains sequences homologous to a number of motifs which are shared among some nuclear genes encoding mitochondrial proteins and therefore may be crucial for the coordinated activation of these genes during mitochondrial biogenesis.
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大肠杆菌中重组表达.
溶解建议
提供的重组人线粒体肌酸激酶2产品形式为无菌的无色溶液.
保存建议
建议将重组人线粒体肌酸激酶2产品整瓶保存于4℃可保存2-4周. 长期保存，请置于-20℃.长期保存，推荐添加载体蛋白 （0.1% HSA or BSA）.请避免反复冻融.
