CKMT1A is in charge of the transfer of high energy phosphate from mitochondria to the cytosolic carrier， creatine. CKMT1A is a member of the creatine kinase isoenzyme family and exists as two isoenzymes， sarcomeric MtCK and ubiquitous MtCK， encoded by separate genes. Mitochondrial creatine kinase arises in two different oligomeric forms: dimers and octamers， unlike the exclusively dimeric cytosolic creatine kinase isoenzymes. Numerous malignant cancers with poor prognosis have displayed overexpression of ubiquitous mitochondrial creatine kinase which is linked to high energy turnover and inability to remove cancer cells through apoptosis.
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大肠杆菌中重组表达.
溶解建议
提供的重组人线粒体肌酸激酶1A产品形式为无菌的无色溶液.
保存建议
建议将重组人线粒体肌酸激酶1A产品整瓶保存于4℃可保存2-4周. 长期保存，请置于-20℃.长期保存，推荐添加载体蛋白 （0.1% HSA or BSA）.请避免反复冻融.
