E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.
应用类型
WB,IHC-P,ICC/IF,FC
免疫原
A synthesized peptide derived from human RING2 / RING1B / RNF2
