Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces an hypoacetylated state of chromatin.
应用类型
WB,IHC-P,ICC/IF
免疫原
A synthesized peptide derived from human macroH2A.1
