Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
应用类型
WB,IHC-F,IHC-P,ICC/IF,ELISA
免疫原
The antiserum was produced against synthesized peptide derived from human eNOS. AA range:1144-1193
