Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
应用类型
WB,ICC/IF,IHC-F,IHC-P,ELISA
免疫原
The antiserum was produced against synthesized peptide derived from human Cleaved-Caspase 1. AA range:161-210
