The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck.
应用类型
IHC-P,IHC-F,ICC/IF,WB,ELISA
免疫原
The antiserum was produced against synthesized peptide derived from human ZAP-70. AA range:460-509
