- 中文名称
MSRA polyclonal antibody
- 英文名字
- MSRA polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS8178
- 产品报价
- ￥询价/50ul
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Protein-bound methionine residues are among the most susceptible to oxidative stress by biological reactive oxygen species (ROS) such as H2O2, hydroxyl radicals and superoxide ions, which result in the formation of methionine sulfoxide, or Met(O). Methionine sulfoxide reductase (MsrA) is an enzyme that catalyzes the thioredoxin-dependent reduction of Met(O) residues in proteins and in methyl sulfoxide compounds. MsrA is a ubiquitously expressed protein which is found in organisms from yeast to man. Mammalian MsrA is most highly expressed in liver, kidney, macrophages, neutrophils, cerebellum and brain neurons. Oxidation of proteins by ROS is associated with oxidative stress and age-related diseases such as Alzheimer’s disease. Recombinant mammalian MsrA retains enzymatic activity, and overexpression of the protein in yeast and human T cells increases their resistance to oxidative stress. Furthermore, MsrA activity decreases in all regions of the Alzheimer’s disease brain. These findings indicate that MsrA plays an important role in protecting cells against oxidative damage and early cell death.
- 应用类型
- WB, IHC, IF/ICC
- 免疫原
- Recombinant full length Human MSRA.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse, Rat
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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