- 中文名称
UGT1A1 polyclonal antibody
- 英文名字
- UGT1A1 polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS7952
- 产品报价
- ￥询价/50ul
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- The human UDP-glucuronosyltransferase 1 (UGT1) locus encodes at least ten UGT1A proteins (UGT1A1-UGT1A10) that play a prominent role in drug and xenobiotic metabolism. Research indicates that nuclear receptors such as pregnane X receptor (PXR), constitutive androstane receptor (CAR) and peroxisome proliferator-activated receptor (PPAR) can regulate UGTs, which may contribute to the tissue-specific expression pattern of UGTs. Deficiency in the expression and/or activity of UGTs may lead to genetic and acquired diseases such as Crigler-Najjar syndrome and Gilbert syndrome. Based on their ability to catalyze the glucuronidation of xenobiotics and endobiotics, UGTs play a critical role in hormonal homeostasis, energy metabolism, bilirubin clearance and xenobiotic detoxification. UDP-glucuronosyltransferase 1A1 (UGT1A), also designated Bilirubin specific UDPGT isozyme 1 (HUG-BR1), is crucial in the conjugation and elimination of toxic zenobiotics and endogenous compounds. Defects in UGT1A1 may cause transient familial neonatal hyperbilirubinemia associated with breast milk, which is characterizied by excessive concentration of bilirubin in the blood, leading to jaundice.
- 应用类型
- WB, IHC, IF/ICC
- 免疫原
- Recombinant full length Human UGT1A1.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse, Rat
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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