- 中文名称
ING4 polyclonal antibody
- 英文名字
- ING4 polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS7889
- 产品报价
- ¥询价/50ul

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- Inhibitor of growth protein (ING) family of nuclear proteins, also designated ING tumor suppressor proteins, inhibit tumor progression by modulating the transcriptional outputs of signaling pathways, which in turn regulates cell proliferation. Members of this family include ING1, ING2, ING3, ING4 and INGX. ING4 localizes to the nucleus and may inhibit tumor progression by adjusting the transcriptional output of signaling pathways which regulate cell proliferation. When complexed with RELA, ING4 can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes. ING4 interacts with HIF prolyl hydroxylase 2 (EGLN1), which represses the activity of hypoxia inducible factor (HIF).
- 应用类型
- WB, IHC
- 免疫原
- Recombinant full length Human ING4.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利

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