Guanine nucleotide exchange factor (GEF for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity.
应用类型
WB
免疫原
Recombinant fusion protein of human RAPGEF4(NP_001093867.1).