- 中文名称
HTRA2 polyclonal antibody
- 英文名字
- HTRA2 polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS7842
- 产品报价
- ￥询价/50ul
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- The human homolog of the E. Coli htrA gene product, HtrA, is identified in osteoarthritic cartilage and is repressed in SV40-transformed fibroblast. The gene encoding HtrA protein is highly conserved among mammalian species and belongs to the serine protease family. The HtrA protein contains an IGF-binding domain and exhibits endoproteolytic activity, including autocatalytic cleavage. HtrA is a secreted protein that is expressed in heterologous systems. HtrA plays a role in the degradation of denatured proteins and cell growth regulation. Human HtrA2 (also designated Omi), a novel member of the HtrA serine protease family, is highly homologous to HtrA (also known as L56 and HtrA1). HtrA2 is a ubiquitously expressed nuclear protease that is capable of autoproteolysis. The HtrA2 protein exists as two polypeptides and as an alternatively spliced form called D-Omi, which is predominately expressed in the kidney, colon and thyroid. Due to a modified PDZ domain, D-Omi does not interact with the known partner of HtrA2, the Mxi2 protein. Like HtrA, HtrA2 is involved in the degradation aberrantly folded proteins during conditions of cellular stress, suggesting that it may possess a chaperone-like role under normal conditions.
- 应用类型
- WB, IHC, IP
- 免疫原
- Recombinant full length Human HTRA2.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse, Rat
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业，Bioworld品牌创立以来拥有10000多种常规产品现货，现有8000多种现货抗体，以及其他IVD原料，蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势，其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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