This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of guanosine triphosphate (GTP). A cytosolic form of this protein is encoded by a different gene and is the key enzyme of gluconeogenesis in the liver. Alternatively spliced transcript variants have been described.
应用类型
WB, IF/ICC, IHC, IP
免疫原
Recombinant fusion protein of human PEPCK/PCK2(NP_004554.2).