- 中文名称
RUVBL1 polyclonal antibody
- 英文名字
- RUVBL1 polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS7815
- 产品报价
- ¥询价/50ul

- 产品说明书
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- 产品新闻

- 背景资料
- Pontin 52 is nuclear matrix protein that is primarily expressed in the nucleus and is also present in the cytoplasm. Pontin 52 is expressed in the nucleoplasm of whole cells, but is not present in the nucleoli. Pontin 52 is also designated RUVBL1, for E. coli RuvB-like 1 protein, or NMP 238, and is the human homolog of rat TIP49. Pontin 52 contains an ATPase/helicase motif and may represent a class of cofactors recruited by transcriptional activation domains that function in diverse pathways. For instance, in vivo, Pontin 52 is complexed with Myc and Reptin 52, which is a Pontin 52 related protein also designated RUVBL2. The interaction of Pontin 52 with Myc is dependent upon a Myc domain essential for oncogenic activity, suggesting that functional Pontin 52 is an essential mediator of Myc oncogenic transformation. The gene encoding human Pontin 52 maps to chromosome 3q21.
- 应用类型
- WB, IHC, IF/ICC
- 免疫原
- Recombinant full length Human RUVBL1.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利

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