EF-1 (elongation factor-1) is a multi-protein complex that is responsible fornthe delivery of aminoacyl-tRNAs to the ribosome. The EF-1 protein complexnis composed of four subunits: EF-1 α, EF-1 β, EF-1 δ and EF-1 γ. EF-1 β is an225 amino acid member of the EF-1 β/EF-1 δ protein family and contains onenGST C-terminal domain. Both EF-1 β and EF-1 δ stimulate the exchange ofnGDP bound to EF-1 α to GTP. Phosphorylation of EF-1 β affects the GDP/GTP exchange rate. Alternative splicing events of the gene that encodes EF-1 β result in three transcript variants that differ only in the 5' UTR.
