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中文名称

NKX2-5 polyclonal antibody

英文名字
NKX2-5 polyclonal antibody
供应商
Bioworld
产品货号
BS7797
产品报价
¥询价/50ul
产品说明书
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背景资料
Nkx-2.5, which is also designated cardiac specific homeobox protein (Csx), is a homeodomain-containing nuclear transcription protein of the Nkx-2 gene family. These transcriptional activators, which include thyroid transcription factor-1 (TTF-1), regulate the expression of tissue specific genes and are required for maintaining the differentiated phenotypes of various lineages. Nkx-2.5 is a homolog to the tinman protein expressed in Drosophila, and is essential for normal cardiovascular development. Expression of Nkx-2.5 during cardiomyogenesis is required for cardiac septation, in which a single atrium and ventricle are separated into four chambers. During embryonic development, Nkx-2.5 is also expressed in the foregut, thyroid, spleen and stomach, while in the adult expression is predominantly restricted to the heart. Mutations that disrupt Nkx-2.5 can result in atrial-septal defects, embryonic lethality and congenital heart disease.
应用类型
WB
免疫原
Recombinant full length Human NKX2-5.
来源宿主
Rabbit
反应性
Human, Mouse, Rat
保存建议
Store at 4
其他
Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
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