Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates.
应用类型
WB, IF/ICC
免疫原
Recombinant fusion protein of mouse C1orf146(NP_877422.2).
