- 中文名称
EIF3E polyclonal antibody
- 英文名字
- EIF3E polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS7779
- 产品报价
- ¥询价/50ul

- 产品说明书
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- 产品新闻

- 背景资料
- The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that lead to 80S ribosomal assembly and, ultimately, translation. The eukaryotic initiation factor-3 (eIF3) scaffolding structure is the largest of the eIF complexes and includes eIF3α, eIF3β, eIF3γ, eIF3δ, eIF3 , eIF3Ω, eIF3η and eIF3θ, all of which function to control the assembly of the 40S ribosomal subunit. Association of eIF3 proteins with the 40S ribosomal subunit stabilizes eIF2-GTP-MettRNAiMet complex association and mRNA binding, and promotes dissociation of 80S ribosomes into 40S and 60S subunits, thereby promoting the assembly of the pre-initiation complex. Overexpression of eIF3 proteins is common in several cancers, suggesting a role for eIF3 proteins in tumorigenesis.
- 应用类型
- WB
- 免疫原
- Recombinant full length Human EIF3E.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利

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